BDBM214808 US9296734, 9
SMILES COc1cnc2c(Nc3ccc(F)c(c3)[C@]3(CF)C[C@H](OC(N)=N3)C(F)(F)F)nccc2n1
InChI Key InChIKey=PCNDBEIQPLJGIC-IFXJQAMLSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 214808
Affinity DataIC50: 372nMT: 2°CAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair